Translation control can shape TP53-dependent cell fate
نویسندگان
چکیده
منابع مشابه
The histone demethylase UTX enables RB-dependent cell fate control.
Trimethylation of histone H3 on Lys 27 (H3K27me3) is key for cell fate regulation. The H3K27me3 demethylase UTX functions in development and tumor suppression with undefined mechanisms. Here, genome-wide chromatin occupancy analysis of UTX and associated histone modifications reveals distinct classes of UTX target genes, including genes encoding Retinoblastoma (RB)-binding proteins. UTX removes...
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ژورنال
عنوان ژورنال: Molecular & Cellular Oncology
سال: 2020
ISSN: 2372-3556
DOI: 10.1080/23723556.2020.1767483